In interregional comparisons of different indicators of quality of perinatal care from the aspect of the importance of revealed differences, it is due to errors of small numbers (number of births per year) better to use instead of frequency analysis the developmental trend of these indicators in the course of several years. From a thus conducted analysis ensues that along with the continual decline of the general perinatal mortality in the majority of regions a marked interregional difference persists in the frequency of very low birth weight neonates as well as in the quality devoted to these neonates. The advantage of regional analyses, as compared with nationwide analyses, is the possibility to assess interrelations between some indicators, e.g. be- tween general early mortality, the frequency of very low birthweight infants and their specific early neonatal mortality which reflects the quality of care of these neonates in the perinatological centre of the catchment area. In the region one of the important tasks of the centre are annual interinstitutional comparisons of quality of care, using selected indicators.

        Key words: