The renal functions impairment caused by intravascular iodinated contrast media applications is not rare complication which occurs after radiodiagnostic and interventional procedures. The renal failure prolongs the hospitalization length, requires temporary or permanent dialysis and increases mortality of these patients. This complication can be prevented and risk of contrast nephropathy development should be minimalized.

        Key words: contrast media – hemodialysis – lactic acidosis – metformin – nephrotoxicity – renal failure – risk factors