This study followed another trial which had the relation to the patients without bone marrow transplantation who were admitted to the intensive care unit due to critical complications. The patients in this study came from the same departments as in the previous study – the Department of Haematology of University Hospital Královské Vinohrady and the Institute of Haematology and Blood Transfusion. The patients were admitted to the intensive care unit in the Department of Anaesthesiology and Intensive Care of University Hospital Královské Vinohrady between January 1999 and December 2000. 15 patients were enrolled in the study (6 patients after autotransplantation and 9 patients after allotransplantation). The authors performed an open and retrospective analysis. The aim of the study was determination of prognostic factors in patients with critical complications. The results are presented in primary formdue to the small number of patients. In patients after autotransplantation the same prognostic factors as in patients without bone marrow transplantation in the previous study were probably involved (the important factors were duration of leucopenia and the extent of multiorgan failure – MOF). The long-term survival rate was 50 %. The survival rate in patients after allotransplantation with critical complications was significantly lower (1 of 9 patients). In this group of patients favourable factors were short interval between critical complication and transplantation and absence of other adverse factors (long lasting leucopenia, MOF syndrome). In patients with adverse prognostic factors the indication of intensive care should be careful and individual and should be made in the cooperation of haematologist (oncologist) and intensivist.

        Key words: bone marrow transplantation – autotransplantation – allotransplantation – critical state – leucopenia – multiorgan failure (MOF)