Iron, Vitamin B12, Folic Acid Levels and Haematological Parameters from Aspect
of Diet and Ethnic Origin
Krajčovičová-Kudláčková M., Blažíček P., Spustová V., Ginter E.
Ústav preventívnej a klinickej medicíny, Bratislava, riaditeľ doc. MUDr. Štefan Nyulassy, DrSc. Nemocnica Ministerstva obrany, Bratislava, riaditeľ plk. MUDr. Juraj Mistrík |
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Summary:
Iron, vitamin B12 and folic acid are essential key nutrients from the haemathological
aspect. Level of the mentioned nutrients and haemological parameters were
determinated in the ethnic Romany (gypsy) minority (men - n = 48, women - n =
71) and compared with the majority group (men - n = 56, women - n = 90). Iron
levels are significantly lower in Romany women; deficient values were found in
29 % vs 14 % in the majority women. Serum iron values in men and deficient level
frequency were not different. Iron deficiency in Romany women is partly associated
with dietary habits (lower consumption of soya and other pulses, intake of
animal iron sources equal or higher in comparison to majority group). Iron losses
due to repeated pregnancies are the second cause of deficient iron levels. Sideropenic
anaemia was detected in 14% Romany women vs 7%in majority (microcytic hypochromic - lower erythrocyte mean volume, lower haemoglobine concentration
in erythrocyte and lower colour concentration). Vitamin B12 levels are similar
in all groups. Vitamin deficiency recorded in 12 % majority women (preferential
consumption of plant food). Romany groups have significantly lower folic acid
levels as a consequence of low or almostno consumption of vegetables,whole grain
product, pulses and fruit. Deficient levels were found 47 % in Romany men, 38 %
in Romany women vs 28 % in majority men and women, respectively. Folic acid
levels correlate positively the educational level (94 % Romany minority with
elementary + continuation vs 27 % majority group). In spite of high folic acid
deficiency macrocytic megaloblastic anaemia was not recorded the Romany
population. Here only the hypothesis is acceptable of a lower folic acid need in
metabolic cycles - remethylation (in theRomanyminority hyperhomocysteinemia
wasnotrecorded)andDNA- cycle in associationwiththeethnicorigin.Conversely
in 8 % of B12 deficient women of the majority group the mean erythrocyte volume
was excessive and there was a higher haemoglobine concentration in erythrocyte
and a low erythrocyte count.
Key words:
iron - vitamin B12 - folic acid - anaemias - Romany (gypsy) population
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