The authors describe a patient with the polyarticular form of pigmented villonodular synovitis associated with many inborn phenotypic abnormalities. The presence of these signs, typical for the Noonan syndrome and the histological finding of giant cells in synovial biopsy are described as Noonan-like/multiple giant cell syndrome.

        Key words: polyarticular form of pigmented villonodular synovitis, Noonan-like/multiple giant cell syndrome, radiotherapy