CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ | |
Journals - Article | |
Česky / Czech version | Čes. a slov. Gastroent. a Hepatol., 2003, roč. 57, č. 3, s. 97-101 |
Biliary Obstruction in Gallstone
Induced Pancreatitis – the Importance of Estimation of Transaminase Activity, Serum Bilirubin
Level, Obstruction Liver Enzymes and Abdominal Ultrasound with Correlation to the Results of
Endoscopic Retrograde Cholangiop ancreatography (ERCP) Hrdlička L.1, Keil R.1, Drábek J.1, Lochmannová J.1, Schwarz J.2 1Interní klinika FN Motol, divize gastroenterologie, endoskopické centrum, Praha 21. chirurgická klinika FN Motol, Praha |
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Summary: Acute biliary pancreatitis is a serious disease with many local and distant complications and steadily high
morbidity. Properly indicated and suitable timed ERCP is a standardised therapeutic option. In our study
group of 104 patients the signs of biliary obstruction assessed by ERCP, biochemical enzymatic changes
(transaminase, alkaline phosphatase and gamaglutamyltranspeptidase serum activity) and ultrasound markers
were correlated. In our group 72 pts (69%) ERCP pathology of the biliary tree was seen. In this group of
72 pts the highest agreement of biliary obstruction signs correlated to transaminase activity (according to
ERCP result in 94%), lower agreement in alkaline phosphatase and gamaglutamyltranspeptidase activity
(89%) and serum bilirubin level (84%).The lowest percentage of agreement of urgent ERCP and abdominals
ultrasound (77%) was seen but this latter seemed to be the most specific method according to data given by
the authors.
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