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  Česky / Czech version Vnitřní lékařství, 50, 2004, č. 10, s. 777 - 780
 
Quality of Therapeutic Control of Hyperlipidemias in Secondary Prevention of Coronary Heart Disease 
Mayer O. Jr.1, Mayer O.Sr.2 

1Centrum preventivní kardiologie II. interní kliniky Lékařské fakulty UK a FN, Plzeň, přednosta doc. MUDr. Jan Filipovský, 2Oddělení klinické farmakologie FN, Plzeň, přednosta doc. MUDr. Otto Mayer, CSc., Sr.
 


Summary:

       Definite evidence has been established, that coronary patients benefit from appropriate therapeutic control of risk profile, as recommended by several Guidelines. However, the impact of these Guidelines on coronary morbidity and mortality is limited by level of its implementation into broad clinical practice and possibility to reach the defined secondary preventive targets with currently available therapeutic resources. We reviewed 6 studies, realized between 1995 and 2000, which was aimed to establish, how many patients with clinical coronary heart disease achieved recommended targets for lipid-lowering treatment. From 10850 cardiac patients examined in these surveys, in average 42.8 % were treated with lipid lowering drugs, but only in 26.8 % and 24.3 % of patients was reached the target level for total and LDL cholesterol, resp. On the other hand use of lipid lowering drugs markedly increased from about 16 - 32 % in 1995 61 - 93 % in 2000, moreover in the same time period the proportion of patients reaching target levels of total cholesterol increased from about 14 - 18 % to 30 - 64 %.

        Key words: Coronary heart disease - Secondary prevention - Hyperlipidemia - Treatment
       

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