CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ | |
Journals - Article | |
Česky / Czech version | Čes. Radiol., 54, 2000, No. 3, p. 188 - 192. |
Correlation of the Planar Scintigraphy and Single Photon Emission
Tomography (SPECT) for Detection of Renal Cortical Defects in Childhood Chroustová D., Palyzová D. 1 , Klánová M. 2 , Kosová B. 3 Klinika nukleární medicíny 3. LF UK, FN Královské Vinohrady, Praha, |
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Summary: Renal scintigraphy using 99mTc DMSA (dimercaptosuccinic acid) is a widely used method for
detection of parenchymal changes. It is considered the „gold standard“ in the diagnosis of acute
pyelonephritis. The mechanism of cortical fixation of the radiopharmaceutical preparation enables
to image the functional renal tissue scintigraphically. Two hours after i.v. administration approxi-
mately 40 - 50 % of the injected amount of the radiopharmaceutical is found in the cortex. Healthy
cortical renal tissue is scintigraphically vizualized as homogeneously distributed radioactivity.
Reduction or a defect of activity is considered a pathological finding. Kidneys can be visualized by
two techniques based on the use of a scintillation camera for planar or for tomographic imaging
based on SPECT.
The aim of this study is the correlation of routine planar scintigraphy and SPECT of the kidneys in
detection of parenchymal changes in children. 191 children (81 boys, 110 girls), aged from 1 month
to 15 years, with suspected renal disease or confirmed diagnosis of renal pathology were examined.
Results: 1. The findings of planar scintigraphy correlated in the majority with that of SPECT, which
determines better the extent and the localization of pathological focus. 2. We prefer based on our
experience planar scintigraphy in children up to 3 years or both these methods. 3. We recommend
routine SPECT examination in older children.
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