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CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ |
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Česky / Czech version | Vnitř. Lék., 46, 2000, No. 7, p. 408 - 412 |
Idiopathic Hypoparathyreoi-
dism with Celiac Disease – Diagnostic and Therapeutic Problem Fryšák Z., Hrčková, Y., Rolinc Z. 1 , Heřmanová Z. 2 , Lukl J. I. interní klinika FN, Olomouc, přednosta prof. MUDr. J. Lukl, CSc. 1 Interní ambulance Valašské Meziříčí 2 Oddělení imunologie FN, Olomouc, přednosta doc. MUDr. E. Weigl, CSc. |
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Summary: A middle-aged woman developed gradually diseases where most probably the common denomina-
tor is an autoimmune process. The authors describe the clinical condition persisting for seven
years, where hypoparathyroidism was associated with coeliac disease which did not respond to
dietary measures. Malabsorption was manifested by a selective block for calcium absorption from
the gut. The impaired conversion of vitamin D2 to D3 is of interest; it has obviously a multifactori-
al etiology. The main problem is the patient´s tendency to respond by tachyphylaxis to oral
vitamin D administration. The only effective therapeutic procedure apart from those listed is so
far parenteral administration of vitamin D3, calcitrol.
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