A middle-aged woman developed gradually diseases where most probably the common denomina- tor is an autoimmune process. The authors describe the clinical condition persisting for seven years, where hypoparathyroidism was associated with coeliac disease which did not respond to dietary measures. Malabsorption was manifested by a selective block for calcium absorption from the gut. The impaired conversion of vitamin D2 to D3 is of interest; it has obviously a multifactori- al etiology. The main problem is the patient´s tendency to respond by tachyphylaxis to oral vitamin D administration. The only effective therapeutic procedure apart from those listed is so far parenteral administration of vitamin D3, calcitrol.

        Key words: Idiopathic hypoparathyroidism - Celiac disease - Malabsorption - Granulomatous