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CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ |
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Česky / Czech version | Prakt. zub. Lék., roč. 53, 2005, č. 1, s. 7–11. |
Titanium Disc Modified with Hydroxyapatite and Zirconia Does not Reveal Signs of Cytotoxicity Teuberová Z.(1), Seydlová M.(1), Dostálová T.(1), Jelínek M.(2), Dvořánková B.(3) (1) Stomatologická klinika 1. LF UK a VFN Praha, přednosta prof. MUDr. J. Mazánek, DrSc. (2) Fyzikální ústav AV ČR, Praha, ředitel Ing. K. Jungwirth, DrSc. (3) Klinika popáleninové medicíny 3. LF UK Praha, přednosta MUDr. L. Brož |
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Summary: The paper deals primarily with the study of biological properties of a model of implant covered with
a thin layer of hydroxyapatite with an intermediate layer of zirconium. Cytotoxicity was evaluated by direct cultivation
with mouse and human fibroblasts. A physical test using X-ray diffraction confirmed that the film is composed
of crystalline hydroxyapatite. The evaluation of the cytotoxicity test and a comparison with controlled samples
cultured in parallel in vitro made it possible to conclude that the material is not cytotoxic audit is
suitable for further experiments in more detail.
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