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CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ |
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Česky / Czech version | Prakt. zub. Lék., roč. 55, 2007, č. 4, s. 67-72. |
Effect of Fluoridated Milk on Progression of Root Surface Lesions in vitro under pH Cycling Conditions Ivančaková R., Harless J. D., Hogan M. M., Wefel J. S. Stomatologická klinika LF UK a FN, Hradec Králové, přednostka doc. MUDr. V. Hubková, CSc. Dows Institute for Dental Research, College of Dentistry, University of Iowa, USA |
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Summary: Summary. The aim of this study was to assess the effect of milk with 0, 2.5 or 5 ppm F- on progression and remineralization of caries-like root-surface lesions using a pH cycling model. The root-surface lesions were crea-ted utilizing a partially saturated lactic acid buffer at pH 4.6. Longitudinal sections were cut through the lesion and analyzed using polarized light microscopy (PLM) and microradiography (MRG). The sections were then coa-ted with an acid resistant varnish, except the outer natural surface that would be exposed to water, milk or fluoridated milk for 2 weeks and cycled in a de- and remineralizing systém. The lesions were characterized again by PLM and MRG after treatment. A significant reduction in lesion progression (33.2%) was found by PLM and MRG after treatment with either non-fluoridated or fluoridated milk when compared to the control group. Using quan-titative MRG, minerál change and distribution in the lesions were recorded. A possible protective effect of fluoridated milk on root surface caries was supported by a reduction in the progression of the lesions and an increase in the minerál content within the lesion.
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