The article deals with the history of foundation and beginnings of the Institute of Physiology of the Medical Faculty of Comenius University in Bratislava. In the school year 1924/25, after the Czechoslovak state university had been founded, the Physiological Institute began its work. The first director was prof. MUDr. Antonín Hanák. Under his leadership the basis of pedagogical and scientific activities in the Institute was established. In the school year 1926/27, Institute moved into the newly built rooms in Sasinková street No 2, where it has been located ever since. Professor Hanák had been working in Bratislava since 1924 till 1930. After his walk-off to Praha, professor MUDr. Vilém Hons became the head of the Institute. In the school year 1936/37 he was elected the dean of the Medical Faculty of Comenius University. He worked in Bratislava till 1939, when he was suspended from the service in the Slovak schools. Both Czech professors founded firm basis of physiology as a subject matter and as a scientific discipline in Slovakia.

        Key words: Institute of Physiology of the Medical Faculty of Comenius University in Bratislava, professor MUDr. A. Hanák, professor MUDr. V. Hons