The aim of this study was to verify a diagnostic value of our enlarged set of visual evoked potentials (VEPs) in patients with possible multiple sclerosis (MS). Only 67 patients (45 females and 22 males, age range 16–60 years, mean age 38 ± 10.6 years) were included in whom simultaneously MRI examination was performed. VEPs examination used pattern-reversal andmotion onset stimuli (with more selective magnocellular system activation). In 39 patients (58%) who were referred for possibleMS, the diagnosis was later confirmed as definite. In this subgroup MRI scanswere abnormal in 79 % of patients and VEPs in 64 %. Although the sensitivity of MRI seems to be higher, in 4 patients with normal MRI VEPs contributed to the diagnostics ofMS(prolonged latency of VEPs). VEPs may provide additional support, particularly in situations in which MRI abnormalities are few or when MRI abnormalities have lesser specificity. Therefore, on the basis of this study,we support to include VEPs examination into the basic set of diagnostic tools in MS.

        Key words: multiple sclerosis (MS), visual evoked potentials (VEPs), magnetic resonance imaging (MRI)