Introduction: The formation of nitrogen bubbles in venous blood is common in a surfacing scuba-diver. Bubbles can pass through a patent foramen ovále (PFO) and can be a source for paradoxical embolization, resulting in the neurological form of decompression sickness (DCS). Methods: We examined 32 scuba divers who had performed more than 100 dives. Right to left shunt detection suggesting the presence of PFO was detected by ubble contrast examination in all divers by means of transthoracic echocardiography (TTE) and transcranial Doppler sonography (TCD). The diagnosis of PFO was then made by means of transoesophageal echocardiography (TEE). Results: Eleven patients had symptoms typical for the neurological form of DCS associated with an ascent. In this group, 91% (10/11) had PFO. In contrast only10% of asymptomatic controls (2/21) had a PFO. TCD confirmed right to left shunting in all patients with PFO. Conclusion: The neurological form of DCS can unmask as yet asymptomatic intracardiac right to left shunting. PFO represents a risk factor for the neurologicalform of DCS in divers. TCD enables easy screening and TEE is a gold standard for PFO diagnostics. Our results demonstrated that PFO detection is a useful cli-nical tool after repeat neurological DCS and should also be ušed for all frequent divers and instructors.

        Key words: patent foramen ovale, scuba diving, decompression sickness