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CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ |
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Česky / Czech version | Vnitřní lékařství, 46, 2000, č. 7, s. 398 – 402 |
Cytokines in Cardiovascular Diseases. Participation in the
Pathogenesis, Effect on Prognosis, Therapeutic Perspectives Pěnička M., Gregor P. Kardiocentrum Fakultní nemocnice Královské Vinohrady a 3. LF UK, Praha, |
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Summary: During the last ten years many papers were published providing evidence of elevated serum
concentrations of different cytokines in the majority of cardiovascular dieseases. Eventually it
was demonstrated that they exert various effects on the heart muscle and vascular wall and thus
have an impact on the patient´s prognosis. Nowadays even a cytokine hypothesis of cardiovascu-
lar diseases exists. The objective of the work is to give an account of contemporary findings on
the importance of cytokines in the pathogenesis of cardiovascular diseases and possilbilities of
therapeutic interventions.
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