Summary: This clinical study assessed the corrosion behaviour of 4 types of nickel- chromium casting alloys commonly ušed in prosthodontic practice. Aim: The aim of study was to verify deposition of nickel and chromium into saliva after the dental product insertion into the mouth, to determine their exact concentrations by ET - AAS method. Further on, the project observed dynamics of metals changing release during certain time period and passive layer formation time. Methods: The research methodology was based on combining clinical study with laboratory testing. Fifteen volunteers delivered saliva samples to sterile tube at designated time. The saliva was handed over at 0 hours, 0.5 hours, 3 hours after delivering simulated denture made of 4 dental alloys widely available on our market. Last sample was taken after 7 days of everyday denture use for at least 3 hours. Individual samples were analyzed by ET - AAS. Results: We collected about 240 saliva samples. Our study determined that chromium release depends on the dental alloy composition and the time after delivering simulated denture. The nickel release depends only on the delivering time, but not on the alloy composition. The highest nickel and chromium release was after 30 minutes, after 7 days the release was approximately the samé as in the 3-hour saliva sample. Conclusions: Our project demonstrated that all analysed dental alloys - Remanium G soft, Wiron 99, Wirolloy and Heraenium NA could be ušed for dental dentures producing. Laboratory testing showed, comparing both nickel and chromium releases, Heraenium should be afraid of in the group of patients with the allergy inclination, compared to Remaium G soft and its lowest nickel and chromium concentrations can be considered as secure as possible.

        Key words: dentistry - dental alloy - corrosion - release of Ni and Cr elements