Germinoma of Pineal and Suprasellar Regions in 11-year Old Boy
Hadravská Š.1, Mukenšnabl P.1, Kohoutek T.2, Kobr J.3, Ferda J.4
Šiklův patologicko-anatomický ústav FN, Plzeň1 přednosta prof. MUDr. M. Michal Ústav histologie a embryologie LF UK, Plzeň2 přednostka doc. MUDr. J. Kočová, CSc. Dětská klinika FN, Plzeň3 přednosta doc. MUDr. F. Stožický, DrSc. Radiodiagnostická klinika FN, Plzeň4 přednosta doc. MUDr. B. Kreuzberg, CSc. |
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Summary:
The case of 11-year old boy is described. At 8th year of his age a hypothyreosis was found. Polydipsia, polyuria,
headache, diplopia and panhypopituitarism occured at 9th year of age. MRI examination of CNS revealed two
tumors localized in the pineal and suprasellar regions. Histological finding of resected part of the tumor at pineal
region revealed a germinoma. The boy was treated with radiotherapy and chemotherapy and complete remission
was induced. Six months later the first relaps arose and the boy was treated with chemotherapy and the second
complete remission was induced. After the next six months a second relapse occurred. Because all possibilities of
therapy were exhausted, the therapy was only symptomatic and during the large infiltration of brain by the tumor
the boy died of bronchopneumonia 21 months after the beginning of the disease.
Key words:
germ-cell tumor, germinoma, pineal and suprasellar tumors
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