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CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ |
| Journals - Article | |
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| Česky / Czech version | Čes. Radiol., 57, 2003, No. 4, p. 184–191. |
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Effect of Samarium-153-EDTMP Treatment in Patients with Painful Bone
Metastases Doležal J., Vižďa J., Čermáková E.1, Horáček J.2, Odrážka K.3, Melichar B.3 Oddělení nukleární medicíny, Fakultní nemocnice, Hradec Králové, přednosta MUDr. ing. J. VižďaOddělení výpočetní techniky, Lékařská fakulta UK, Hradec Králové1 vedoucí prof. MUDr. P. Stránský, CSc. Katedra interních oborů, Lékařská fakulta UK, Hradec Králové2 vedoucí prof. MUDr. J. Malý, CSc. Klinika onkologie a radioterapie, Fakultní nemocnice, Hradec Králové3 přednosta doc. MUDr. J. Petera, PhD. |
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Summary: Aim: Bone is a common site of metastatic disease and is the most common site of metastatic spread
in breast cancer and prostate cancer.The pain is themost important consequence of bone metastases
and is present in most of the patients. Radiotherapy represents one of effective therapeutic options
in the palliation of bone pain. Currently, radiation may be delivered either by external irradiation
(loco-regional, half-body) or intravenous administration of bone-seeking therapeutic radiopharmaceuticals
as is Samarium-153-EDTMP. This radiopharmaceutical produces beta radiation, and is
concentrated in areas of enhanced osteoblastic activity.
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