Summary:
An unusual testicular tumour with features of both sex cord tumour with annular tubules and
large-cell calcifying Sertoli cell tumour is described. The tumour occurred in a 20-year-old man in
the left testis as a 1 cm-measuring well circumscribed solitary lesion. Histologically, it showed
sertoliform annular tubules with included eosinophilic nodules as well as isolated large cells and
cords to sheets of the cells lying in a sclerosing stroma. A few psammomatous microcalcifications
were seen. In contrast to similar cases reported before, the patient did not have any signs of
Peutz-Jeghers syndrome, feminization or other complex dysplastic syndromes. The case indicates
that tumours of this type may occur in phenotypically normal patients like pure large cell calcify-
ing Sertoli cell tumours or ovarian sex-cord tumours with annular tubules. It further supports
a close histogenetic relationship between these two entities.
Key words:
large-cell calcifying Sertoli cell tumour - Peutz-Jeghers syndrome - Sertoli cell tumour
- sex- cord tumour with annular tubules - testis
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