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  Klin. Biochem. Metab., 7 (28), 1999, No. 4, p. 264–266
 
Surface Microstructure of Hair in some Children’s Diseases 
Vaněk M. 1 , Schramlová J. 2 , Hanzlová J. 3 , Procházková D. 4 

1 Department of Zoology, Mendel University of Agriculture and Forestry, Brno 2 National Institute of Public Health, Prague 3 Department of Anatomy, Faculty of Medicine, Masaryk University, Brno 4 Research Institute of Child’s Health, Brno, Czech Republic
 


Summary:

       The study deals with the surface microstructure of hair in some children’s diseases, nam ely Netherton’s syndrome, Refsum disease, Herter disease and Menkes’ syndrome. Hair from 5 patients was prepared and compared with hair from healthy individuals. The supradermal part of hair was photograp hed using a scanning electron microscope (SEM). In all 4 diseases, similar destructive morphological changes were observed, namely hair torsion, detachment of cuticular scales (cells) up to partial shedding, and deformation of cuticular cells. None of these destructive morphological changes were observed in hair from healthy individuals.

        Key words: Netherton’s syndrome, Refsum disease, Herter disease, Menkes’ syndrome, SEM.
       

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