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CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ |
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Česky / Czech version | Trans. Hemat. dnes, 13, 2007, No. 1, p. 12–15. |
Arelationship of serum
imunoglobulin free light chain levels measurement to multiple myeloma staging Pika T.1, Zemanová M.1, Minařík J.1, Schneiderka P.2, Bačovský J.1, Ščudla V.1 1III. interní klinika LF UP a FN, Olomouc 2Oddělení klinické biochemie FN, Olomouc |
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Summary: The study is aimed to evaluate of serum imunoglobulin free light chain levels measurement in multiple myeloma and
their relationship to each stage not only of traditional Durie – Salmon staging system, but also to recently established
International Staging System and South West Oncology Group staging system. The results of analysis showed
that serum free light chain levels corelate with each stage of staging systems based on dynamic indices (serum albumin
and ß2-microglobulin) more expressively, than traditional Durie –Salmon staging system. The study also confirmed
dependency of serum free light chain levels upon renal function.
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