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  Česky / Czech version Klin. Biochem. Metab., 11 (32), 2003, No. 2, p. 91–92.
 
Determination of hTau Protein and β-amyloid(1–42) in the Cerebrospinal Fluid 
Bekárek V.1, Pidrman V.2, Mareš J.3 

1OKBL FN Olomouc 2Klinika psychiatrie FN Olomouc 3Neurologická klinika FN Olomouc
 


Summary:

       Concentration of hTau protein and β-amyloid(1–42) were determined in cerebrospinal fluid (CSF) of patients with dementia. Genetic assessment of apolipoproteine E were compared with clinical diagnosis of this group of patients. Possibility of diagnosing Alzheimer’s disease and excluding vascular reasons of old age dementia by examination of hTau protein and β-amyloid(1–42) in CSF are discussed.

        Key words: Alzheimer’s disease, β-amyloid(1–42), hTau proteine, apolipoproteine ApoE.
       

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