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  Česky / Czech version Čes. a slov. Oftal., 59, 2003, No. 2, p. 91 - 97
 
Duo-Bonharen - a New Viscoelastic Preparation 
Al-Farzai A.*, Novák J.**, Hubálek F.***, Češková P.***, Kvasnička J.*, Langr F.**** 

*Oční klinika, Fakultní Nemocnice a Lékařská fakulta v Hradci Králové Univerzity Karlovy v Praze, přednosta prof. MUDr. P. Rozsíval, CSc. **Oční oddělení Krajské nemocnice Pardubice a Ústavu zdravotnických studií UniverzityPardubice, přednosta doc. MUDr. J. Novák, CSc. ***Výzkumné oddělení Contipro a.s. Ústí nad Orlicí, ředitel RNDr. V. Velebný, CSc. ****Fingerlandův stav patologické anatomie, Fakultní Nemocnice a Lékařská fakulta v Hradci Králové Univerzity Karlovy v Praze, přednosta prof. MUDr. I. Šteiner, CSc.
 


Summary:

       Thepaper discusses preclinical tests of anewviscoelastic preparation forophthalmosurgery. Experiments revealed that preparationDuo-Bonharen whichcontains hyaluronic acid prepared by bacterial fermentation is suited for clinical tests. After a 24-hour interval following administration into the anterior chamber it does not raise intraocular pressure. In experiments it has no side-effects on the eye. The dispersed form in a higher concentration (5 %) adheres verywell to ocular tissues and protects them adequately during surgery. The cohesive form in an optimal concentration (1.5 %) can be rapidly removed from inside the eye. The properties of Duo-Bonharen in experiments are comparable with similar viscomaterials which are used. The new viscoelastic material Duo-Bonharen appears suitable for clinical tests in particular for cataract surgery.

        Key words: hyaluronic acid, viscomaterial, microsurgery of the eye
       

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