CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ | |
Journals - Article | |
Česky / Czech version | Čes. a slov. Oftal., 59, 2003, No. 2, p. 91 - 97 |
Duo-Bonharen - a New Viscoelastic Preparation Al-Farzai A.*, Novák J.**, Hubálek F.***, Češková P.***, Kvasnička J.*, Langr F.**** *Oční klinika, Fakultní Nemocnice a Lékařská fakulta v Hradci Králové Univerzity Karlovy v Praze, přednosta prof. MUDr. P. Rozsíval, CSc. **Oční oddělení Krajské nemocnice Pardubice a Ústavu zdravotnických studií UniverzityPardubice, přednosta doc. MUDr. J. Novák, CSc. ***Výzkumné oddělení Contipro a.s. Ústí nad Orlicí, ředitel RNDr. V. Velebný, CSc. ****Fingerlandův stav patologické anatomie, Fakultní Nemocnice a Lékařská fakulta v Hradci Králové Univerzity Karlovy v Praze, přednosta prof. MUDr. I. Šteiner, CSc. |
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Summary: Thepaper discusses preclinical tests of anewviscoelastic preparation forophthalmosurgery.
Experiments revealed that preparationDuo-Bonharen whichcontains
hyaluronic acid prepared by bacterial fermentation is suited for clinical tests.
After a 24-hour interval following administration into the anterior chamber it
does not raise intraocular pressure. In experiments it has no side-effects on the
eye. The dispersed form in a higher concentration (5 %) adheres verywell to ocular
tissues and protects them adequately during surgery. The cohesive form in an
optimal concentration (1.5 %) can be rapidly removed from inside the eye. The
properties of Duo-Bonharen in experiments are comparable with similar viscomaterials
which are used. The new viscoelastic material Duo-Bonharen appears
suitable for clinical tests in particular for cataract surgery.
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