The author presents the čase reports of two patients suffering from chronic viral hepatitis C. The article describes the complex and long-term treatment of this disease, which is associated with frequent adverse effects. Attention is paid to health and sociál aspects. The disease and its treatment very often necessitate sickness leave or even disability in some cases. The treatment is lead by a specialist (hepatologist), however, the generál practitioner plays an irreplaceable role in coordinating the treatment with other specialists and in solving the sociál consequences of the disease

        Key words: chronic viral hepatitis C, generál practitioner, health-social aspects