Objective: The aim of this article is the comprehensive information about different bulking subs- tances and their use for the treatment of genuine stress urinary incontinence in women. Design: The review sumarizes various materials used for this purpose, methods of their applica- tion, possible complications and results of clinical studies of implants. Setting: Department of Obstetrics and Gynaecology of Charles University and Faculty Hospital Bulovka takes part in the development of the new metacrylate of Czech origine. Subject and Method: Current scientific literature as listed in the article. Conclusion: Implants seem to be a useful alternative method in the treatment of the genuine stress incontinence in women.

        Key words: urinary incontinence, sphincter deficiency, periurethral implant, injection therapy, collagen, autologous fat, teflon, DiHA, macroplastique, methacrylate