Unexpected high serum level of CA 125 in male patient
suffering from metastatic papillary carcinoma: a case report
Klapková E.1, Průša R.1, Kukačka J.1, Kotaška K.1, Škapa P.2
1Department of Clinical Biochemistry and Pathobiochemistry, Charles University 2nd Medical School, University Hospital Motol, Prague, Czech Republic 2Department of Pathology and Molecular Medicine, Charles University 2nd Medical School, University Hospital Motol, Prague, Czech Republic |
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Summary:
This report describes a case of male patient with metastatic papillary carcinoma of unknown primary origin with
unusual high levels of CA 125. Laboratory tests in serum and plasma (urea, creatinine, uric acid, sodium, potassium,
total bilirubin, ALT, AST, GMT, ALP, C-reactive protein, and glucose) were normal except C-reactive protein (57.6 mg/l).
Computer tomography scan showed tumorous formations situated in the area of both kidneys. According to the literature
we performed more detailed laboratory investigation (CEA, CA 125, CA 15-3, CA 19-9, AFP) and we found only serum
level of CA 125 significantly elevated (> 600 kU/l). The results of recent studies suggest that CA 125 might be useful as
a serum tumor marker also in patients with other carcinomas apart ovarian cancer.
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