It is generally accepted that the complement component profile in inflammatory renal diseases is abnormal. As glomerular morphology is pathologically altered, there might be leakage of some macromolecular proteins into the renal tubular lumen leading to further damage and immune reaction. Hereby, we present a preliminary test to identify the complement component and related fragments as immune reaction mediators in urine samples of fourteen children with renal glomerular diseases proved by needle biopsy: hereditary nephritis (HN) i.e. Alport’s syndrome, immunoglobulin-M nephropathy (IgMN), mesangial proliferative glomerulonephritis (MesPGN), membranous glomerulonephritis (MGN), and immunoglobulin-A nephropathy (IgAN). Unfortunately we did not evaluate the results statistically due to very limited number of patients in each classification subgroup.

        Key words: immunoblotting, rare urinary proteins.