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CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ |
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| Česky / Czech version | Klin. Biochem. Metab., 10/31, 2002, No. 2, p. 103-107 |
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PAPP-A - Maternal Serum Marker of Down Syndrome during the First Trimester of Pregnancy Fialová L.1, Malbohan I. M.1, Soukupová J.2, Mikulí`ková L.1, Krofta L.3 11. ústav lékařské chemie a biochemie 1. LF UK, Praha 2Ústav klinické biochemie 1. LF UK, Praha 3Ústav pro péči o matku a dítě, Praha |
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Summary: Pregnancy-associated plasma protein A (PAPP-A) and free R-HCG belong to the major biochemical markers of prenatal screening of congenital developmental abnormalities. The authors characterise shortly PAPP-A, present imunochemical methods of assessment and the importance in prenatal diagnostice.
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