In the etiopathogenesis of spontaneous intracranial haemorrhages (SICH) a number of risk factors is involved. The objective of the prospective study was to evaluate the role of modifiable metabolic RF in different subtypes of SICH. Methods: The authors examined a group of 105 patients with SICH, incl. 88 with haemorrhages with an intracerebral localization (ICH) and 17 with a subarachnoid/intraventricular localization (SAH/IVH). The following metabolic RF and their combinations were monitored: arterial hypertension (AH), diabetes mellitus/impaired glucose tolerance (DM/IGT), obesity and dyslipidaemia. For evaluation of the statistical significance of the results the χ2 test was used. Results: The incidence of the following metabolic RF was significantly more frequent in patients with ICH than in SAH/IVH: AH in 64.8% vs 23.5% (p=0.002), DM/IGT in 36.4% vs. 5.9% (p=0.013), hypercholesterolaemia (HCH) in 72.7% vs. 47.1% (p=0.037) and a combination of AH+DM/IGT in 26.1% vs.0% (p=0.017),AH+HCH in 51.1% vs. 17.6%(p=0.011),DM/IGT+HCH in 23.9% vs.0% (p=0.024). Conclusion: AH, DM/IGT and HCH incl. mutual combinations play in our population the most important part in the etiopathogenesis of spontaneous ICH.

        Key words: spontaneous intracranial haemorrhage, spontaneous intracerebral haemorrhage, subarachnoid haemorrhage, risk factors