The Juxtaposition of the Measurement of the Left Ventricle Ejection Fraction
by Radionuclide versus X-ray Ventriculography in Patients with Coronary
Artery Disease
Doležal J.1, Vižďa J.1, Solař M.2, Čermáková E.3
1Oddělení nukleární medicíny LF a FN, Hradec Králové přednosta MUDr. ing. J. Vižďa 2I. interní klinika LF a FN, Hradec Králové přednosta prof. MUDr. J. Vojáček, DrSc. 3Ústav lékařské biofyziky LF a FN, Hradec Králové přednosta prof. MUDr. P. Stránský, CSc. |
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Summary:
Aim: As a part of the grant „Contrast-enhanced MRI versus thallium myocardial perfusion
SPECT in detection of viable left ventricle myocardium before coronary artery
bypass graft (CABG)“ the reproducibility of rest equilibrium ECG gated radionuclide
ventriculography (RNV) was evaluated. Since all patients in this study underwent
coronary angiography with X-ray ventriculography, the authors could perform a comparison
of left ventricle ejection fraction (EF) between radionuclide and X-ray ventriculography.
Material and method: Fourteen patients (12 men, 2 women, being aged 42-74, with
median of 55 years) with coronary artery disease underwent coronary angiography
and X-ray ventriculography. After a few weeks RNV (500 cycles, matrix 64 x 64, 24 frame
per cycle, low-energy all purpose collimator, left anterior oblique view) was performed.
In vivo labeled red blood cells by 99mtechnetium (750 MBq) were used as
a radiopharmaceutical. The acquisition was made by digital gamma camera Helix Elscint
(LEAP collimator). After 30 minutes the authors started next RNV with the same
patient and the same acquisition parameters. That means the acquisition was made
twice.
Results: The juxtaposition of measurement of the left ventricle ejection fraction (RNV ejekčversus
X-ray ventriculography) by limits of agreement was performed. Reproducibility
of RNV was very good (4% on both sides). The agreement between EF 1 RNV and
X-ray ventriculography (20% on both sides) or EF 2 RNV and X-ray ventriculography
(22% on both sides) was not very good.
Conclusion: The reproducibility of RNV was very good. Poor agreement of the measurement
of left ventricle ejection fraction between RNV and X-ray ventriculography
was detected.
Key words:
radionuclide ventriculography – X-ray ventriculography
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