Objecive: Testing the depression, anxiety and/or frustration differences between women and men coming for IVF treatment, depending on cause of infertility. Design: Prospective study. Setting: Assisted Reproduction Centre, Gynecology and Obstetrics Department, 1 st Medical Faculty of Charles University, Apolinářská 18, Prague 2, 128 00 Czech Republic. Methods:66 infertile couples before IVF treatment were subjected to Becks Depression Inventory, State-Trait Anxiety Inventory and Dusin frustration test. Obtained test results were statistically processed and correlated to male of female factor of infertility. Results:The depression and anxiety scores in couples with female infertility factor were significantly higher (p < 0.05) in women than in man, while among couples with male infertility factor the results of men and women were not significantly different. Conclusion: Women probably more suffer from guilty feeling in case of couple infertility than their partners. This phenomenon was expressed through higher depression and anxiety degree in women in couples with female infertility factor.

        Key words: psychology, IVF, anxiety, depression, gender, male, female infertility factor