Summary:
First results of multilocus sequence typing (MLST) for characterization of 29 invasive Streptococcus
pyogenes strains isolated in the Czech Republic in the first half of 2003 are presented. None of 16
emm types detected among the study strains showed sequence type (ST) variability. The MLST
results are indicative of differences between the strains causing serious diseases in the Czech
Republic and those isolated in other countries. In seven strains, four new STs with known alleles in
new combinations, ST134, ST308, ST336, ST340, and one new ST with three as yet undescribed alleles
(gki 91, murI 65 and yqiL 60), ST341, were described. These newly described STs were submitted to
the web-based reference MLST database for S. pyogenes.
Key words:
invasive group A streptococci – clonal analysis – MLST – streptococcus.
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