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  Česky / Czech version Čs. Patol., 35, 1999, No. 2, p. 45 - 54
 
Structural Correlations of Splenic Tissue in Idiopathic Thrombocytopenic Purpura of Adults (ITP) 
Jirásek A. (1) , Salaj P. (1) , Vorlová Z. (1) , Kolářová M. (2) 

 


Summary:

       Immunologic activation of the splenic white pulp seemed to be an important feature of the structural changes in the 8 splenectomized patients with ITP. However, destruction of the plate- lets with CD 16+ monocytes was the most prominent change in the Billroth’s cords of the splenic red pulp. Classical NK cells did not play an important role in platelets destruction.

        Key words: idiopathic thrombocytopenic purpura - splenic pulp - monocytes
       

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