The Influence of Inflammatory Bowel Disease on the Period of Conceiving
Pintérová Kolesárová M., Pintér M., Rejchrt S., Douda T., Tachecí I., Kopáčová M., Bureš J.
II. interní klinika lékařské fakulty UK a FN, Hradec Králové, Subkatedra gastroenterologie, přednosta prof. MUDr. J. Malý, CSc. |
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Summary:
Introduction: Crohn’s disease (CD) and ulcerative colitis (UC) influence women fertility in many ways.
Objective: We tried to determine the influence of the inflammatory bowel disease on conceiving. The date
of the diagnosis, localisation, form and activity at time of conception were involved.
Design: Retrospective study.
Methods: We assessed data from 81 patients with inflammatory bowel disease. 56 patients were
diagnosed before conceiving (41 with CD, 15 with UC), 25 patients were diagnosed after pregnancy (14
with CD, 11 with UC). We assessed the period of conceiving (in months) depends on previous abdominal
operation, localisation, form and activity of the disease at time of conception. The data were obtained
from the questionnaire and hospital cards.
Results: The previous abdominal operation, the diagnosis, localisation, and the form of the disease did not
influence the period necessary to conceive in patient with inflammatory bowel disease. The anoperineal
localisation and activity of Crohn’s disease at the time of conception extended the period necessary to conceive.
Conclusion: Fertility of the patients with Crohn’s disease depends on the activity of the disease at time of
conception and anoperineal involvement. Previous abdominal operation does not influence the fertility.
Key words:
Crohn’s disease, ulcerative colitis, fertility, operation, activity of the disease
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