More than 80 years have elapsed since the discovery of insulin. The submitted paper analyzes the main contemporary trends of the development of insulin therapy which comprise the develop-ment of new insulin analogues and their use in modified insulin regimes, the development of preparations for inhalatory or oral administration, new techniques of administration and new ways of self-monitoring. The author mentions also non-traditional forms of insulin therapy such as transplantation of insulin producing tissue and in the conclusion she discusses trends of insulin administration in subjects without diabetes.

        Key words: Insulin - Diabetes mellitus - Insulin treatment