The authors evaluated the intubating conditions,haemodynamic parameters and possible signs of histamine release after application of the recommended intubating dose of cis-atracurium (3x ED95,i.e.0.15 mg.kg -1 ).At 120 sec after application of the intubating dose the intubating conditions were assessed as good or excellent in 56 of 60 patients (93.3%).Haemodynamic effects were mild only;no patient had any sign of histamine release. Cis-atracurium is suitable alternative to atracurium.It has better cardiovascular stability,lower histamine release and therefore less side effects than atracurium.

        Key words: cis-atracurium –muscle relaxants –intubating conditions –side effects