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CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ |
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Česky / Czech version | Vnitř. Lék., 48, 2002, No. 10, p. 993 - 995 |
Syndrome of Inadequate Antidiuretic Hormone Secretion in
Non-differentiated Small Cell Lung Cancer Gřiva M., Kubánek J. Interní oddělení, Nemocnice Kroměříž, přednosta prim. MUDr. P. TřeštíkHyponatrémie je jednou z nejčastějších poruch elektrolytového metabolismu. Jednou z příčin |
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Summary: Hyponatraemia is one of the most frequent disorders of the electrolyte metabolism. One of the
causes may be also the syndrome of inadequate antidiuretic hormone secretion. The cause of
increased production of antidiuretic hormone can be not only a pathological condition affecting
the hypothalamo-pituitary system but also ectopic production of antidiuretic hormone or peptide
with the same effect on the distal portion of the nephron. A classical type of malignant tumour
where the syndrome of inadequate antidiuretic hormone secretion develops is small cell lung
cancer. It is also known that some pharmaceutical preparations stimulate the output of antidiuretic
hormone or potentiate its effect.
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