Subclinical hypothyroidism is comparatively frequent disorder with incidence between 3t o 7 % in the general population; in females over 60 it can exceed 10 %. There is no unequivocal view on the clinical significance of the syndrome; however, it may correspond with increased risk of atherosclerosis and its complications. Especially in elderly women, screening for subclinical hypothyroidism is recommended with possible hormone replacement according to given criteria. Decision about the therapy of subclinical hypothyroidism should be done together with cardiologist, psychiatrist or neurologist in order to correct possible clinical impacts and prevent further manifestations.

        Key words: subclinical hypothyroidism, atherosclerosis, ischaemic heart disease, lipoproteins.