The authors examined retrospectively the frequency of NSAID use by patients with gastroduode- nal ulcer without HP. The objective was to evaluate whether the use of NSAID is the predomina- ting factor in the development of ulceration in subjects with HP negative ulceration. The group comprised 525 patients with confirmed presence of H, incl. 52 who used NSAID. From the results ensues that the incidence of ulcerous lesions with HP negativity and NSAID medication is signifi- cantly higher than in subjects who use NSAID and suffer from a confirmed HP infection.

        Key words: Helicobacter pylori – NSAID.