Emergency departments are generally the first treatment places for the trauma victims. Evaluating the traumatised patients by objective criteria are of great importance in diagnosis, treatment and prognosis. This prospective study was conducted at the Medical School of Erciyes University. Blood levels of Ceruloplasmin, Haptoglobulin and Transferrin, which are known as acute phase reactants, were obtained. 60 trauma patients were included in this study. 19 (31.6 %) females and 41 (68.4 %) males. 15 patients were operated. 4 (26 %) patients died during the postoperative follow-up period. When compared with ceruloplasmin values obtained on all of the groups this they were statistically significant except that two day-control group. All of the haptoglobulin groups were statistically significant. When compared with transferin values obtained on first-two day, first-seven day and two-seven day, they were statistically significant (P<0.05). As a results, We might say that the changes in the blood levels of all three biochemical parameters are related to the severity of the trauma. Taking advantage of all such changes we might predict both the severity of the trauma and the prognosis of traumatic episodes. This gives us an opportunity to define better strategies for the follow-up and treatment of our trauma patients.

        Key words: Ceruloplasmin - Haptoglobulin - Transferrin - Traffic accidents