This article reviews the method of Guided Bone Regeneration. This method was derived from the biological principle of Guided Tissue Regeneration. There is new therapeutic concept for the regeneration of bone defects caused by restriction of the root apex, osteotomy or cystectomy. Other suitable indications occur in periodontology, oral implantology, and in case of alveolar crest astrophy – augmentation. The most suitable biomaterials used in this process are reabsorbable collagen Bio-Gide membranes and natural bone mineral Bio-Oss. This combination of materials has been used by the authors to stimulate the repair of bone defects for several years, and it gives a favourable results.

        Key words: guided bone regeneration – bio-materials