The epidemie of nicotine dependence presents serious problém of contemporary medicíně and public health. The most effective approach to treatment of nicotine dependence is combination of pharmacotherapy and psychotherapy. Pharmacotherapy has its own advertising campaign due to producers and we haveenough information about this approach. On the other side we know very little information about psychotherapy of nicotine dependence and its effective and systematic application is often rather exception. The article deseribes basic constructs of Transtheoretical model of behavioral changes and its application on sample of smokers. The aim of present study is to introduce an integration psychotherapy approach to treatment of nicotine dependence.

        Key words: Transtheoretical model, processes of change, stages of change, motivation to smoking cessation, nicotine dependence, psychotherapy.