Objective: The authors demonstrate the case of a rare vulvar angiomyxoma in a 57-year-old female. Design: Case report. Settings: Department of Obstetrics and Gynecology, Medical Faculty Charles Uni Prague and Faculty Hospital, Hradec Králové. Subject and Method: A rare case of pedunculated angiomyxoma involving the vulva of a 57- year-old female.is reported. Complete excision of the tumor was performed. Conclusion: Angiomyxoma is a rare locally infiltrative neoplasm of the vulvovaginal region, perineum and pelvis. Notorious recurring after surgical resection is due to its infiltrative border that makes it difficult to attain a cleared margin at the time of resection.

        Key words: angiomyxoma, vulva