Acute headache is very frequent symptom in clinical practice which is mostly associated with benign viral or bacterial upper respiratory tract infections. But headache can be infrequently an alarming symptom of life threatening disease and urges on prompt diagnostic and therapeutic measurements (intracranial hemorrhage, tumor, hydrocephalus, CNS and ENT infections). Authors illustrate the review with a case of rare but threatening disease.

        Key words: acute headache, sphenoid sinusitis