Nodular Cervical Metastases of Spinocellular
Carcinoma of Oropharynx and Pharynx (Part 1)
Praženica P., Lacman J.1, Holý, R., Navara M., Voldřich Z.
Otorinolaryngologické oddělení, Ústřední vojenská nemocnice Praha, přednosta plk. MUDr. M. Navara Radiodiagnostické oddělení, Ústřední vojenská nemocnice Praha, přednosta pplk. MUDr. F. Charvát 1 |
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Summary:
The authors present a prospective study aimed at the evaluation of palpation, ultrasonography
(USG), computing tomography (CT) and nuclear magnetic resonance (MRI) in the diagnostics of cervical
metastases of spinocellular carcinoma (SCC) of oropharynx and pharynx. The study included 49
patients with SCC of oropharynx or pharynx over the period of 2.5 years with the following criteria for
cervical metastases: 1. Maximum transverse dimension of lymphatic node > 15 mm in the sector I and > 10
mm in other sectors. 2. L/T quotient < 2 (ratio between the maximum longitudinal and maximal or minimal
transverse diameter of the lymphatic node). 3. A group of three or more mutually unbounded lymphatic
nodes of the size between 8 and 10 mm. 4. Central necrosis. 5. Extranodal dissemination. The sensitivity
of palpation proved to be 53% and the specificity 67%. USG reached sensitivity and specificity 74%
alike according to the criterion of size, sensitivity of 79% and specificity of 93% was reached according to
L/T quotient and sensitivity of 90% and specificity of 98% was reached according to central necrosis.
A common combination of all USG criteria revealed sensitivity of 85% and specificity of 87%. In selecting
the criterion of the size CT and MRI proved to reach sensitivity of 71% and 78%, respectively and specificity
of 90% and 85%, respectively. The central necrosis displayed sensitivity of 88% and 89% and specificity
of 99% and 96% for CR and MRI, respectively. In the combination of all criteria the authors reached sensitivity
of 75% for CT and 78% for MRI and specificity of 87% for CT and 85% of MRI. The authors arrived
at the conclusion that the diagnostics of nodular cervical metastases on the basis of palpation is insufficient.
The results obtained by USG diagnostics are reliable. The diagnostic value of L/T quotient and central
necrosis is high. The diagnostic possibilities of CT and MRI proved to be similar. A common combination
of all criteria proved to be best for all techniques. The presumption of a rapid improvement in the
detection of nodular cervical metastases on the basis of CT and MRI examinations has not been confirmed
and USG proved to be even more useful in some parameters of evaluating nodular affection.
Key words:
cervical dissection, nodular cervical metastases, palpation, ultrasonography, computing tomography,
nuclear magnetic resonance.
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