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  Česky / Czech version Vnitř. Lék., 48, 2002, No. 3, p. 255-258
 
Brugada Syndrome 
Mádle A., Kratochvíl Z., Polívková A. 

II. interní klinika LF UK Plzeň a Fakultní nemocnice, Plzeň, přednosta doc. MUDr. Jan Filipovský, CSc.
 


Summary:

       On the case of a patient who had medical care on account of a febrile disease diagnosed as pleuritis the authors draw attention to a relatively new pathological unit described as the „Bruga- da syndrome“. It is a genetically conditioned anomaly of sodium channels, which, when fully expressed, is manifested by a picture resembling right bundle branch block, elevation of ST segment in leads V1 - V3 and the occurrence of malignant ventricular arrhythmias or sudden death without structural heart disease. Neither the reported patient nor his family suffered from arrhythmias. The authors present however a typical electrocardiographic picture ad positive test with ajmaline, a substance which by blocking sodium channels can frequently induce latent and variable changes.

        Key words: Brugada syndrome - Sudden death - Right bundle branch block - Segment elevation
       

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