Peripheral Nerve Injury and the Degree of Motor
Involvement in Parkinson’s Disease: A Correlation Study
1Chovancová Z., 1Kaňovský P., 1Nestrašil I., 2Dufek J., 1Nevrlý M., 1Otruba P.
1Neurologická klinika LF UP a FN – Centrum pro diagnostiku a léčbu neurodegenerativních onemocnění, Olomouc 2Privátní poliklinika Dr. Kropáče, neurofyziologická laboratoř, Brno |
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Summary:
Background. The aim of the study was to validate a hypothesis about the presence of a concomitant
peripheral nerves injury in patients suffering from neurodegenerative disorders. The study was focused
on the correlation between motor involvement in Parkinson’s disease and peripheral nerves injury.
Methods and Results. 23 patients suffering from Parkinson’s disease, which was diagnosed in terms of
strict UK-PDBB criteria, were examined. There were 14 men (mean age: 57 years, mean age at the
disease onset: 51years, mean disease duration: 7 years, mean duration of dopaminergic treatment:
4 years) and 9 women (mean age: 67 years, mean age at the disease onset: 63 years, mean duration of
disease: 4 years, mean duration of dopaminergic treatment: 1 year). Polyneuropathy was clinically
present and confirmed using EMG examination in 10 patients (43.5 %), 5 men and 5 women.
Conclusions. Our observation indicates that the neurodegenerative process can be involved not only in
the degeneration of central nervous system, but also in the peripheral disorders in this population.
Key words:
Parkinson’s disease, polyneuropathy, electromyography, correlation.
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