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CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ |
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| Česky / Czech version | Klin. Biochem. Metab., 15 (36), 2007, No. 2, p. 82–84. |
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Solitary extramedullary plasmacytoma: diagnostics and therapy Vošmik M.1, Maisnar V.2 1Klinika onkologie a radioterapie, Univerzita Karlova v Praze, Lékařská fakulta v Hradci Králové a Fakultní nemocnice Hradec Králové2Oddělení klinické hematologie, II. interní klinika, Univerzita Karlova v Praze, Lékařská fakulta v Hradci Králové a Fakultní nemocnice Hradec Králové |
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Summary: Solitary extramedullary plasmacytoma (SEP) is a very uncommon malignant disease. Eighty percent of SEP occurs in
head and neck region. Other localizations of the disease are often accidental histopathological findings.
The main therapeutic modality in SEP of head and neck region is radiotherapy, which enables to achieve local control
in 80–100% cases. The dose of radiotherapy and clinical target volume are discussed, mainly the necessity of lymph
node irradiation considering the treatment toxicity. Intensity-modulated radiotherapy is a new radiotherapy approach
which offers a treatment toxicity reduction.
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