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CZECH MEDICAL ASSOCIATION J. Ev. PURKYNĚ |
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Česky / Czech version | ACTA CHIRURGIAE PLASTICAE 46, 1, 2004, pp. 19 - 22 |
TOTAL ANTIOXIDANT CAPACITY OF SERUM AND
PROGNOSTIC INDICES IN PATIENTS WITH BURN TRAUMA Frišman E.1, Drozda D.2, Šipulová A.3, Rácz O.4, Babík J.1 1Clinic of Burns and Reconstructive Surgery, 2Department of Clinical Biochemistry, Hospital Ko ice – a ca Ltd., Ko ice – aca, 3Institute of Experimental Medicine, 4Institute of Pathophysiology, Medical School, a f ri k University, Ko ice, Slovakia |
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Summary: Burn trauma leads to increased production of reactive oxygen species and compromises the antioxidant systems.
The aim of present study was to assess the total antioxidant capacity of plasma (TAC) in burn patients and evaluate
its usefulness in clinical practice through analysis of association between TAC and indices of patient prognosis.
We investigated TAC in 48 adults and 27 children with severe burn trauma and in 26 healthy controls. TAC was
measured on the admission and every week thereafter until discharge or death of patients. The prognosis of the
patients was evaluated by the Baux Index and the Abbreviated Burn Severity Index (ABSI).
TAC was significantly decreased in both groups with burn trauma as compared with the controls and the decrease
was a long lasting event. Significant indirect negative correlation was found between BSAB and TAC values
measured in the later phase of injury. In adults an indirect correlation was found between ABSI and the lowest
TAC measured on the 7th day or later. Correlations between TAC values and Baux Index were absent both in
adults and in children.
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