Intraperitoneal Placement of Composite Material –
Polyester Mesh with Coat of Polyurethane in Experimental Study
Chobola M.1, Vobořil Z.1, Hadži Nikolov D.2
1Chirurgická klinika FN a LF UK, Hradec Králové, přednosta prof. MUDr. Z. Vobořil, DrSc. 2Fingerlandův patologicko-anatomický ústav FN a LF UK, Hradec Králové, přednosta prof. MUDr. I. Šteiner, CSc. |
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Summary:
Introduction: Polyester and polypropylene are currently the most frequently materials for repair of abdominal wall hernias.
Most of the mesh materials used intraperitoneally in repair of hernias lead to considerable adhesion formation, as well as the
resultant bowel obstruction and intestinal fistula formation. Some newer composite products can reduce risk of adhesion
formation. The aim of this experimental study is testing properties of patch, composite structure, characterised by the
association of a non-woven textile structure made from polyester multifilaments, and a fine coat of polyurethane on one side,
placed intraperitoneally in rat.
Materials and methods: The experiment was carried out with 21 laboratory rats. Laboratory animals were divided into
3 groups – 7 animals in a group. In the first group the check-up laparotomy was realized the 7th day, in the second group the
14th day and in the third group the 28th day after the intraperitoneal implantation of a composite mesh. All animals were
sacrificed and adhesion scoring and histological evaluation of tissue specimens with implanted mesh were done.
Results:Amacroporous polyester mesh component supported an early and huge fibrous proliferation with a good adhesion
onto the abdomen wall. On the other hand, a microporous polyurethane layer led to the creation of a fibrous pocket. During
the check-up laparotomy, the larger adhesion of omentum to the fibrous layer, covering the polyurethane side of implanted
mesh, were located in most laboratory rats – in all the groups.
Conclusion: We can presume that the protective polyurethane layer does not eliminate risk of adhesion formation in rat.
Key words:
hernia – polyester – polyurethan – composite material – intraperioneal implantation – adhesion formation
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